Lung Disease News - Lung Disease News

February 28, 2018August 24, 2022
Rare Disease Day: How You Can Help Raise Awareness
Social Clips
Rare Disease Day takes place on the last day of February. The worldwide event has gained a lot of traction ... Read more
February 27, 2018
6 Dos and Don’ts for Living Well With a Chronic Illness
Social Clips
In response to how to cope with a chronic illness, many reply with the following statement: “there is no rulebook, ... Read more
February 22, 2018
The Many Benefits of Self-Care & Finding Balance
Social Clips
In a society that appears to glorify multitasking, after-hours meetings, excessive screen time and full schedules, it’s more important than ... Read more
February 21, 2018February 21, 2018
Prometic’s PBI-4050 Regulates 2 Receptors Key to Fibrosis Development, Study Shows
Idiopathic Pulmonary Fibrosis, News
PBI-4050, Prometic Life Sciences’ lead small molecule therapy candidate, targets a new antifibrotic pathway involving two receptors that play opposite roles ... Read more
February 21, 2018
The Invisible Impact of Trauma on Pulmonary Fibrosis Patients
Social Clips
With the exception of using supplemental oxygen, pulmonary fibrosis (PF) is an invisible disease for the most part. Like other ... Read more
February 20, 2018February 20, 2018
Synthetic Proteins That Mimic Enzyme HYAL2 May Be Potential Therapeutic Strategy for PF, Researchers Say
Idiopathic Pulmonary Fibrosis, News
Researchers found that an enzyme previously linked only to cell metabolism is capable of reaching the nucleus of lung fibroblasts ... Read more
February 20, 2018
Considering Lung Transplantation: The Pros & Cons
Social Clips
When the only “known” cure for idiopathic pulmonary fibrosis (IPF) is removing the diseased lungs and replacing them with new ... Read more
February 19, 2018February 19, 2018
Phase 2 Trial Shows KD025 Has Potential to Prevent Lung Function Decline in IPF
Idiopathic Pulmonary Fibrosis, News
An investigative drug developed by Kadmon called KD025 was shown to be safe and effective to prevent lung function decline in patients ... Read more
February 16, 2018February 16, 2018
Short-acting Asthma Relievers Linked to Female Infertility
Asthma, News
Women who use only short-acting asthma medications take longer to become pregnant than non-asthmatic women or women taking long-acting medications, ... Read more
February 15, 2018
Why You Should Consider Joining Our Online Forum
Social Clips
The Pulmonary Fibrosis News forums launched a week ago! Many members have shared the PF forums with their own personal ... Read more
February 15, 2018February 15, 2018
NICE Opinion Limiting Esbriet to UK Patients with Moderate to Severe IPF Disappoints, patientMpower Says
Idiopathic Pulmonary Fibrosis, News
The digital healthcare company patientMpower expressed disappointment at the opinion issued by an influential U.K. healthcare advisory group to limit the ... Read more
February 14, 2018February 14, 2018
FDA Approves Vertex’s Symdeko to Treat CF Patients 12 and Older
Cystic Fibrosis
The U.S. Food and Drug Administration (FDA) has approved the third targeted therapy developed by Vertex Pharmaceuticals for patients with ... Read more

Pulmonary Fibrosis

February 21, 2018February 21, 2018
Prometic’s PBI-4050 Regulates 2 Receptors Key to Fibrosis Development, Study Shows

PBI-4050, Prometic Life Sciences’ lead small molecule therapy candidate, targets a new antifibrotic pathway involving two receptors that play opposite roles in fibrosis development, researchers found. ... Read more
February 20, 2018February 20, 2018
Synthetic Proteins That Mimic Enzyme HYAL2 May Be Potential Therapeutic Strategy for PF, Researchers Say

Researchers found that an enzyme previously linked only to cell metabolism is capable of reaching the nucleus of lung fibroblasts and once there, halting the ... Read more
February 19, 2018February 19, 2018
Phase 2 Trial Shows KD025 Has Potential to Prevent Lung Function Decline in IPF

An investigative drug developed by Kadmon called KD025 was shown to be safe and effective to prevent lung function decline in patients with idiopathic pulmonary fibrosis (IPF), ... Read more

Asthma

February 16, 2018February 16, 2018
Short-acting Asthma Relievers Linked to Female Infertility

Women who use only short-acting asthma medications take longer to become pregnant than non-asthmatic women or women taking long-acting medications, a new international research study ... Read more
January 25, 2018January 25, 2018
CDC Studies Asthma Burden on U.S. Economy — and Numbers are Striking

Asthma costs the U.S. economy nearly $82 billion a year, say researchers at the Centers for Disease Control and Prevention (CDC). Using data from the ... Read more
January 16, 2018January 16, 2018
Fasenra Approved in EU for Treatment of Severe Eosinophilic Asthma

The European Commission has approved Fasenra (benralizumab) as an add-on maintenance treatment in patients with severe eosinophilic asthma. The approval, announced by therapy developer AstraZeneca and its global research and development ... Read more

Bronchiectasis

February 1, 2018February 1, 2018
FDA Gives Aradigm Recommendations for Resubmitting Bronchiectasis Therapy Application

The U.S. Food and Drug Administration has given Aradigm a list of suggestions for resubmitting an application for regulatory review of its bronchiectasis therapy Linhaliq. A review board ... Read more
January 18, 2018January 18, 2018
FDA Advisory Committee Does Not Recommend Approval of Inhalant Linhaliq

The Antimicrobial Drugs Advisory Committee (ADAC) of the U.S. Food and Drug Administration (FDA) did not recommend approval of Aradigm’s Linhaliq for the treatment of ... Read more
December 4, 2017December 4, 2017
FDA Advisory Group Sets Jan. 11 Review Date for Linhaliq, Potential Non-CF Bronchiectasis Therapy

A committee of the U.S. Food and Drug Administration (FDA) will meet next month to review an application for Linhaliq to be approved for the treatment of ... Read more

BRONCHIOLITIS

March 7, 2017March 7, 2017
Treatment Seen to Lessen Fibrotic Scarring That Causes Lung Transplants to Fail

Treatment may be able prevent the progressive accumulation of scar tissue (fibrosis) in newly transplanted lungs that eventually cause those organs to fail, researchers at the University of ... Read more
January 18, 2017January 18, 2017
European Researchers Awarded €29M Grant to Assess RSV Lung Infections

Specialists in respiratory syncytial virus (RSV) from the RSV Consortium in Europe received a grant worth 29 million euro (equal to about $30.8 million American) to ... Read more
April 5, 2016April 5, 2016
In Infants with Bronchiolitis, Study Points to Need for Re-evaluation of Clinical Care, Diagnostic Tools

In a new study, researchers at The Hospital for Sick Children (SickKids) in Toronto, Canada, analyzed the suitability of pulse oximetry as a decision-making tool ... Read more

CHRONIC BRONCHITIS

May 17, 2017May 17, 2017
Respiratory Infections Linked to Increased Risk of Heart Attack

New research conducted at the University of Sydney in Australia found that the risk of having an acute myocardial infarction, commonly referred to as a heart ... Read more
February 17, 2017February 17, 2017
European Environmental Federation Hails EU Air-standards Compliance Move

The non-profit European Environmental Bureau (EEB) is hailing a European Commission move toward legal action against France, Germany, Italy, Spain and the United Kingdom for failing ... Read more
November 8, 2016November 8, 2016
Can Certain Odors Worsen Airway Diseases? Researchers Think So

Olfactory receptors, a group of proteins that are activated by certain odors in the nose, can also be found in bronchi cells, where they regulate ... Read more

COPD

February 7, 2018February 7, 2018
Remote Monitoring Could Help COPD Patients, but More Studies Needed, Researchers Conclude

Devices that remotely monitor COPD patients’ conditions could help improve their outcomes, a study suggests. A Cedars-Sinai Medical Center team said there were signs in the ... Read more
January 29, 2018January 29, 2018
COPD Care at Home Rather Than Hospital Boosts Patient Outcomes, Canadian Study Finds

Moving chronic obstructive pulmonary disease (COPD) patients from hospitals to their homes could improve the sustainability of Canada’s health system while improving individual outcomes, says the ... Read more
November 27, 2017November 27, 2017
New York’s Montefiore Einstein Center Launches Lung Transplant Program

New York City’s Montefiore Einstein Center for Heart & Vascular Care has received interim approval from the United Network for Organ Sharing (UNOS) to launch its new ... Read more
September 15, 2017September 15, 2017
Identification of Regenerative and Scar-Forming Cells May Lead to New Lung Therapies, Study Reports

Researchers have identified two types of lung cells, one with regenerative features and the other with scar-forming characteristics, according to a study published in the ... Read more
September 11, 2017September 11, 2017
Study Links Fungus Antibodies with Development of Bronchiectasis in COPD Patients

Researchers have linked the presence of antibodies against the Aspergillus fumigatus (A fum) fungus with the development of bronchiectasis in people with COPD. The study, “Sensitization to Aspergillus ... Read more
August 29, 2017August 29, 2017
Three Share British Lung Foundation Grant for Lung Disease Research

Toby Maher, MD, a professor at Imperial College London and based at the National Heart and Lung Institute, is one of three researchers who were awarded the prestigious ... Read more

CYSTIC FIBROSIS

February 14, 2018February 14, 2018
FDA Approves Vertex’s Symdeko to Treat CF Patients 12 and Older

The U.S. Food and Drug Administration (FDA) has approved the third targeted therapy developed by Vertex Pharmaceuticals for patients with cystic fibrosis (CF). Symdeko can now ... Read more
February 5, 2018February 5, 2018
Vertex Selects VX-659 and VX-445 for Two CF Triple Combo Regimens

Vertex Pharmaceuticals has selected two of its next-generation correctors, VX-659 and VX-445, for Phase 3 trial development as part of two triple combination regimens for the ... Read more
January 12, 2018January 12, 2018
European Union Approves Orkambi Use for Children 6-11 Years Old

The European Commission has granted Vertex Pharmaceuticals an extension of the marketing authorization for Orkambi (lumacaftor/ivacaftor) to include children 6-11 years old who have cystic fibrosis ... Read more
January 9, 2018January 9, 2018
Proteostasis’ Planned Trial of Triple Combo CF Therapy Supported By Advocacy Groups in US, Europe

The drug development arms of two leading cystic fibrosis (CF) organizations, one in the U.S. and one in Europe, have endorsed Proteostasis Therapeutics’ coming trial ... Read more
January 3, 2018January 3, 2018
Top 10 Lung Disease Stories of 2017

During 2017 Lung Disease News provided you with daily coverage on research, clinical trials and other developments in lung diseases. Here are our top 10 stories of ... Read more
December 12, 2017December 12, 2017
Kalydeco Seen As Safe in Treating CF in Young Children, Ages 1 to 2, Study Data Show

Kalydeco (ivacaftor) was shown to be safe and well-tolerated in 1- and 2-year-old children with cystic fibrosis (CF), based on data from a Phase 3 trial, ... Read more

EMPHYSEMA

January 18, 2017January 18, 2017
European Researchers Awarded €29M Grant to Assess RSV Lung Infections

Specialists in respiratory syncytial virus (RSV) from the RSV Consortium in Europe received a grant worth 29 million euro (equal to about $30.8 million American) to ... Read more
November 8, 2016November 8, 2016
Can Certain Odors Worsen Airway Diseases? Researchers Think So

Olfactory receptors, a group of proteins that are activated by certain odors in the nose, can also be found in bronchi cells, where they regulate ... Read more
September 15, 2016September 15, 2016
Homogeneous Emphysema Patients Could Benefit from Zephyr Endobronchial Valve, Study Shows

Pulmonx recently announced positive results from the IMPACT (NCT02025205) study assessing the company’s proprietary Zephyr endobronchial valve (EBV), showing that patients with homogeneous emphysema benefit from the ... Read more
September 8, 2016September 8, 2016
New Lung Analysis Platform Rapidly Identifies Patients Eligible for Endobronchial Valve Treatment

Pulmonx recently announced that its StratX Lung Analysis Platform is commercially available in countries requiring CE mark (Conformité Européne, a mark that proves a product ... Read more
August 17, 2016August 17, 2016
Pulmonary Problems Can Plague Childhood Cancer Survivors Through Adult Life

Pulmonary complications can mount in childhood survivors of cancer for as long as 25 years after initial diagnosis, and have a substantial impact on their daily ... Read more
July 12, 2016July 12, 2016
Researchers Say Lung-targeted Gene Therapy May Improve Treatments for Inherited Diseases

A team of researchers from the Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center (BMC) developed a new treatment approach using ... Read more

IDIOPATHIC PULMONARY FIBROSIS

February 21, 2018February 21, 2018
Prometic’s PBI-4050 Regulates 2 Receptors Key to Fibrosis Development, Study Shows

PBI-4050, Prometic Life Sciences’ lead small molecule therapy candidate, targets a new antifibrotic pathway involving two receptors that play opposite roles in fibrosis development, researchers found. ... Read more
February 20, 2018February 20, 2018
Synthetic Proteins That Mimic Enzyme HYAL2 May Be Potential Therapeutic Strategy for PF, Researchers Say

Researchers found that an enzyme previously linked only to cell metabolism is capable of reaching the nucleus of lung fibroblasts and once there, halting the ... Read more
February 19, 2018February 19, 2018
Phase 2 Trial Shows KD025 Has Potential to Prevent Lung Function Decline in IPF

An investigative drug developed by Kadmon called KD025 was shown to be safe and effective to prevent lung function decline in patients with idiopathic pulmonary fibrosis (IPF), ... Read more
February 15, 2018February 15, 2018
NICE Opinion Limiting Esbriet to UK Patients with Moderate to Severe IPF Disappoints, patientMpower Says

The digital healthcare company patientMpower expressed disappointment at the opinion issued by an influential U.K. healthcare advisory group to limit the use of Esbriet (pirfenidone, marketed ... Read more
February 13, 2018February 13, 2018
Pulmonary Fibrosis Foundation Creates Website to Help Patients Find Clinical Trials

The Pulmonary Fibrosis Foundation has created an online Clinical Trial Finder to help pulmonary fibrosis patients search for trials to enroll in. Foundation officials said the site allows ... Read more
February 12, 2018February 12, 2018
Vanderbilt Team to Test Antiviral Therapy for Pulmonary Fibrosis

A Vanderbilt University team will study whether adding a commonly used antiviral medicine to standard treatments for idiopathic pulmonary fibrosis can help stop or reverse the disease’s ... Read more

LUNG CANCER

February 6, 2018February 6, 2018
Single Blood Test Screens for 8 Cancer Types, Helps Spot Tumor Location

A new blood test can screen for eight cancer types and help spot the tumor location, a recent study from Johns Hopkins Kimmel Cancer Center shows. ... Read more
January 10, 2018January 10, 2018
Insurance Coverage Affects Treatment Given Small-cell Lung Cancer Patients in US, Study Shows

Insurance status for people in the U.S. with non-metastatic small-cell lung cancer (SCLC) can determine both the type of treatment they are given and their ... Read more
January 5, 2018January 5, 2018
US Continues Its Decades-long Drop in Cancer Mortality Rates

Cancer mortality rates in the United States have continued to steadily decline, with 2.4 million fewer cancer-related deaths reported in 2015 than in 1991, when rates ... Read more
January 3, 2018January 3, 2018
Top 10 Lung Disease Stories of 2017

During 2017 Lung Disease News provided you with daily coverage on research, clinical trials and other developments in lung diseases. Here are our top 10 stories of ... Read more
December 20, 2017December 20, 2017
Aggressive Treatment of IPF Patients with Lung Cancer Rarely Best Option, Experts Say

A group of clinician-reseachers with expertise in lung diseases suggest in a commentary that people with both idiopathic pulmonary fibrosis (IPF) and lung cancer are best managed with ... Read more
December 18, 2017December 18, 2017
Genentech’s New Combo Therapy Improves Progression-free Survival in Advanced Non-small Cell Lung Cancer

Progression-free survival (PFS) was improved in patients with advanced non-squamous non-small cell lung cancer (NSCLC) using a combination of Avastin (bevacizumab), Tecentriq (atezolizumab), and chemotherapy ... Read more

PNEUMONIA

October 12, 2017October 13, 2017
Vibativ Displays More Punch Against Bacteria Than Other Antibiotics, Studies Show

Vibativ (telavancin) displays more punch against the Staphylococcus aureus bacteria that is involved in lung diseases than other antibiotics it has been tested against, according to presentations in ... Read more
August 18, 2017August 18, 2017
Vaccination Against Lung Pathogens Vital for People with Lung Disease, American Lung Association Reminds

August is National Immunization Awareness Month, and the American Lung Association is reminding adults with serious lung diseases that the Centers for Disease Control and ... Read more
August 8, 2017August 8, 2017
Aridis Is Enrolling Patients in Pivotal Trial of Its Antibiotic-resistant Pneumonia Therapy Aerucin

Aridis Pharmaceuticals has begun enrolling patients in what it says will be a pivotal clinical trial of its antibiotic-resistant pneumonia therapy Aerucin. The trial will cover Aerucin’s ... Read more
May 17, 2017May 17, 2017
Respiratory Infections Linked to Increased Risk of Heart Attack

New research conducted at the University of Sydney in Australia found that the risk of having an acute myocardial infarction, commonly referred to as a heart ... Read more
February 14, 2017February 14, 2017
Antibiotics May Make Newborns More Susceptible to Pneumonia, Researchers Say

Widespread use of antibiotics in newborns may interfere with gut bacteria, increasing the risk of the infants developing pneumonia, according to a study. The research, ... Read more
February 2, 2017February 1, 2017
BU Medical School Researcher Awarded $5.9M to Study Biology of Pneumonia

A professor at Boston University School of Medicine (BUSM) has been awarded a $5.9 million Outstanding Investigator grant from the National Institutes of Health (NIH) ... Read more

PULMONARY HYPERTENSION

January 19, 2018January 19, 2018
Eiger BioPharmaceuticals Discontinues Development of Ubenimex in PAH After Disappointing Results

Eiger BioPharmaceuticals will discontinue the development of ubenimex as a therapy for pulmonary arterial hypertension (PAH) due to disappointing results in the Phase 2 LIBERTY clinical ... Read more
January 11, 2018January 11, 2018
Bellerophon Enrolls First Patient in Study of INOpulse to Treat PH Linked to Interstitial Lung Disease

A Phase 2b clinical study evaluating INOpulse as a treatment for pulmonary hypertension (PH) associated with interstitial lung disease (PH-ILD) enrolled the first patient, Bellerophon ... Read more
November 15, 2017November 15, 2017
Canadian Association Conducting Purple Challenge Campaign During PH Awareness Month

The Pulmonary Hypertension Association of Canada is conducting a Life in Purple Challenge this month as part of its efforts to mark November as Pulmonary Hypertension Awareness Month. ... Read more
September 5, 2017September 5, 2017
SteadyMed’s NDA for Trevyent to Treat PAH Refused by FDA; More Information Needed

The U.S. Food and Drug Administration rejected SteadyMed’s new drug application (NDA) for Trevyent (treprostinil), a treatment for pulmonary arterial hypertension (PAH). According to the FDA’s ... Read more
July 25, 2017July 25, 2017
ZappRx Implements Specialty Medication Prescribing Platform at 2 Pulmonary Medical Centers

Harbor-UCLA Medical Center in Torrance, California, and Phoenix-based Arizona Pulmonary Specialists — the largest U.S. private practice treating pulmonary hypertension — now offer a digital platform designed by ... Read more
July 18, 2017July 18, 2017
Mount Sinai, Theragene Collaborate to Develop New Gene Therapy for Pulmonary Hypertension

Researchers from New York’s Mount Sinai have partnered with Theragene Pharmaceuticals to further develop a new airway-delivered gene therapy for pulmonary hypertension (PH). After showing promising results in animal studies, this new therapy ... Read more

SCLERODERMA

January 11, 2017January 11, 2017
Molecule Seen to Be Marker of Sclerosis-linked Lung Disease, Its Severity

In the majority of patients with systemic sclerosis (SSc), interstitial lung disease (ILD) is the leading cause of death. New research shows that plasma levels ... Read more
May 26, 2016May 26, 2016
Promising Scleroderma Clinical Trial May Improve Hand Dysfunction

Cytori Therapeutics provided a recent update on results from clinical trials assessing the use of Cytori Cell Therapy (ECCS-50) in the treatment of scleroderma-related hand dysfunction. The presentation was made ... Read more
May 3, 2016May 3, 2016
Cytori Updates Phase 3 Scleroderma STAR Trial, Enrolls 60th Patient

Cell therapy company Cytori Therapeutics announced that its Phase 3 STAR clinical trial has enrolled and treated its 60th patient, reaching 75 percent of the target enrollment ... Read more
May 2, 2016May 2, 2016
Cumberland Pharmaceuticals to Begin Development of Scleroderma Drug Vasculan

Cumberland Pharmaceuticals recently added Vasculan to its clinical portfolio. The company has began the clinical development of Vasculan (ifetroban) oral capsule for the treatment of ... Read more
April 29, 2016April 29, 2016
Fibrocell’s Gene Therapy for Localized Scleroderma Designated an Orphan Drug by FDA

Fibrocell Science, Inc., recently announced that the U.S. Food and Drug Administration (FDA) has designated FCX-013 an orphan drug for the potential treatment of localized scleroderma, a chronic ... Read more
April 20, 2016April 20, 2016
Small Protein M10 Could Help Prevent Lung Fibrosis, According to Animal Study

A new study from researchers in South Carolina report that a small protein called M10 peptide might prevent fibrosis (scarring) in people with systemic sclerosis (SSc). ... Read more

Rare Disease Day: How You Can Help Raise Awareness

6 Dos and Don’ts for Living Well With a Chronic Illness

The Many Benefits of Self-Care & Finding Balance

Prometic’s PBI-4050 Regulates 2 Receptors Key to Fibrosis Development, Study Shows

The Invisible Impact of Trauma on Pulmonary Fibrosis Patients

Synthetic Proteins That Mimic Enzyme HYAL2 May Be Potential Therapeutic Strategy for PF, Researchers Say

Considering Lung Transplantation: The Pros & Cons

Phase 2 Trial Shows KD025 Has Potential to Prevent Lung Function Decline in IPF

Short-acting Asthma Relievers Linked to Female Infertility

Why You Should Consider Joining Our Online Forum

NICE Opinion Limiting Esbriet to UK Patients with Moderate to Severe IPF Disappoints, patientMpower Says

FDA Approves Vertex’s Symdeko to Treat CF Patients 12 and Older

Pulmonary Fibrosis

Asthma

Bronchiectasis

BRONCHIOLITIS

CHRONIC BRONCHITIS

COPD

CYSTIC FIBROSIS

EMPHYSEMA

IDIOPATHIC PULMONARY FIBROSIS

LUNG CANCER

PNEUMONIA

PULMONARY HYPERTENSION

SCLERODERMA