Cystic Fibrosis

November 13, 2015November 13, 2015

Potential New Cystic Fibrosis Therapy, CTP-656, Begins Phase 1 Study

Cystic Fibrosis, News

Concert Pharmaceuticals, Inc., a clinical stage biopharmaceutical company focused on utilizing its DCE Platform® (deuterated chemical entity platform) to create novel small molecule drugs, recently announced that it has initiated a Phase ... Read more

November 9, 2015November 9, 2015

In CF, Manipulating a Gene Triggers Inflammatory Response

Cystic Fibrosis, News

Findings from a recent study published in the Journal of Inflammation showed that knockdown of the CFTR gene of two intestinal epithelial cell lines triggers an inflammatory response, which may ... Read more

November 9, 2015November 9, 2015

Microorganism in CF, Other Bacterial Infections May Have Met Its Match

Cystic Fibrosis, News

Researchers from the University of Florida Health (UF Health) system have developed new medicinal compounds that may have important implications for cystic fibrosis patients who suffer from biofilm-associated bacterial infections. Biofilms ... Read more

November 9, 2015November 9, 2015

Pediatric Lung Transplants May Increase With Change in Rules

Cystic Fibrosis, News

New policies to facilitate international cooperation in sharing pediatric donor lungs could result in doubling the number of lung transplants in young patients in the United States, according to a study ... Read more

November 3, 2015November 24, 2015

CF Fertility Rates Research Personal for University of Alabama at Birmingham Investigator

Cystic Fibrosis, News

For Sigrid Ladores, Ph.D., a pediatric nurse practitioner and an Assistant Professor at the University of Alabama at Birmingham School of Nursing, investigating reproductive health concerns of adolescents and young ... Read more

November 2, 2015November 5, 2015

Mannitol Shown to Not Enhance Anti-bacterial Effect of Tobramycin in Treating Pseudomonas Aeruginosa

Cystic Fibrosis, News

In a new study, researchers found that mannitol co-treatment with the antibiotic tobramycin did not enhance the antibiotic’s bacterial killing effect in a Cystic Fibrosis (CF) model. The research paper, ... Read more

October 30, 2015November 5, 2015

OrPro’s Cystic Fibrosis Treatment Theradux Receives US Patent

Cystic Fibrosis, News

OrPro Therapeutics, Inc. a company developing Theradux (ORP-100), a new inhaled treatment designed to treat cystic fibrosis (CF) and other obstructive diseases characterized by thickened, stiff and adhesive mucus, recently announced ... Read more

October 27, 2015November 5, 2015

Vertex and CRISPR Therapeutics Partner to Advance Gene Therapies for Cystic Fibrosis, Sickle Cell

Cystic Fibrosis, News

Vertex Pharmaceuticals, Inc., and CRISPR Therapeutics announced a new strategic research partnership focused on utilizing the CRISPR-Cas9 gene editing platform in the potential discovery and development of new gene therapies. The companies plan to focus ... Read more

October 23, 2015November 5, 2015

In Cystic Fibrosis, P. aeruginosa May Carry Distinctive Genetic Signature

Cystic Fibrosis, News

Researchers identified a genetic signature due to the inflammatory response in cystic fibrosis (CF) human bronchial epithelial cells infected with Pseudomonas aeruginosa (P. aeruginosa) bacterium that may one day lead ... Read more

October 20, 2015November 5, 2015

Bacteria’s Adaptive Changes to Cystic Fibrosis May Contribute to Chronic Lung Disease Development

Cystic Fibrosis, News

In a recent study, Canadian and U.S. scientists investigated the effects of Pseudomonas aeruginosa lasR mutations on inflammatory responses in an epithelial cell line, mice and CF patients. Their study, entitled ... Read more