Idiopathic Pulmonary Fibrosis

October 25, 2017October 25, 2017

Global Blood Therapeutics Scraps Its Effort to Develop GBT440 as a Treatment for IPF

Disappointing clinical trial results have prompted Global Blood Therapeutics to scrap its program to develop GBT440 as a treatment for idiopathic pulmonary fibrosis. GBT440 increased patients’ lung oxygen levels, but not enough ... Read more

October 24, 2017October 24, 2017

Ofev Improves IPF Patients’ Lung Function Over the Long Term, Trial and Extension Show

Idiopathic Pulmonary Fibrosis, News

Long-term treatment with Boehringer Ingelheim‘s Ofev (nintedanib) improved the lung function and reduced the flare-ups of people with idiopathic pulmonary fibrosis, results of a Phase 2 clinical trial and its extension show. ... Read more

October 18, 2017October 18, 2017

New Blocker of TGF-β1 Shows Promise as Potential Therapy for IPF Patients

Idiopathic Pulmonary Fibrosis, News

Blocking TGF-β1 — a known signaling pathway involved in tissue fibrosis — by compounds called trihydrophenolics halted fibrosis development and tissue stiffness in animal models of pulmonary fibrosis, new research shows. The ... Read more

October 18, 2017October 18, 2017

Pulmonary Rehabilitation Improves Patients’ Ability to Exercise and Quality of Life, Study Reports

Idiopathic Pulmonary Fibrosis, News

Pulmonary rehabilitation programs can improve exercise capacity and health-related quality of life in patients with interstitial lung diseases (ILDs), including those with pulmonary fibrosis, a study shows. These findings support ... Read more

October 5, 2017October 5, 2017

Depression and Anxiety Influence Pulmonary Fibrosis Patients’ Quality of Life, Study Reports

Idiopathic Pulmonary Fibrosis, News

Depression and anxiety significantly influence the quality of life of people with idiopathic pulmonary fibrosis, although not their hospitalization or death rates, a study found. IPF patients are susceptible to ... Read more

October 3, 2017October 3, 2017

Baseball Legend, Country Singer to Join Renowned Scientists at Pulmonary Fibrosis Summit

Idiopathic Pulmonary Fibrosis, News

A New York Yankees legend and a country music singer will join renowned scientists in speaking at the Pulmonary Fibrosis Foundation’s international PFF Summit 2017 in Nashville, Nov. 9-11. Top physicians and researchers ... Read more

October 2, 2017October 2, 2017

Prometic Gets FDA Approval to Start Phase 2/3 Trial of PBI-4050 in IPF Patients

Idiopathic Pulmonary Fibrosis, News

Prometic Life Sciences announced that PBI-4050, its investigational therapy for idiopathic pulmonary fibrosis (IPF), has been cleared by the U.S. Food and Drug Administration (FDA) to enter a Phase 2/3 combination-treatment trial in the ... Read more

September 21, 2017September 21, 2017

IPF World Week 2017: Listening for the Sounds of IPF May Lead to Earlier Diagnosis

Idiopathic Pulmonary Fibrosis, News

Recognizing how difficult it is to diagnose idiopathic pulmonary fibrosis, Boehringer Ingelheim has created a detection system based on sounds coming from the lungs. Because the sounds of people with the disease ... Read more

September 20, 2017September 20, 2017

FibroGen’s Pamrevlumab Slows Lung Function Decline in IPF Patients, Trial Results Show

Idiopathic Pulmonary Fibrosis, News

Lung function decline in patients with idiopathic pulmonary fibrosis (IPF) was slowed by the investigational drug pamrevlumab, according to the results from a Phase 2b clinical trial. The results were presented ... Read more

September 15, 2017September 15, 2017

Identification of Regenerative and Scar-Forming Cells May Lead to New Lung Therapies, Study Reports

COPD, Idiopathic Pulmonary Fibrosis, News

Researchers have identified two types of lung cells, one with regenerative features and the other with scar-forming characteristics, according to a study published in the journal Cell. The research team ... Read more