severe asthma

March 27, 2017March 27, 2017

HMGB1 Protein Causes Lung Airways of People with Severe Asthma to Narrow, EU Study Finds

Asthma, News

Researchers have discovered that the active form of the HMGB1 protein narrows the lung airway in people with severe asthma, providing a potential target for new treatments. Their study, “HMGB1 is upregulated ... Read more

May 27, 2016May 27, 2016

Severe Asthma Reduced in Phase 3 Benralizumab Tests

Asthma, News

AstraZeneca recently announced that the new severe asthma medicine benralizumab met the primary endpoints in two Phase 3 registration trials. Findings of the trials called SIROCCO and CALIMA, revealed that the monoclonal antibody compound ... Read more

March 28, 2016March 28, 2016

FDA Approves Teva’s Asthma Drug Cinqair as Add-on Treatment

Asthma, News

Teva Pharmaceutical Industries recently announced the approval of Cinqair (reslizumab) injection by the U.S. Food and Drug Administration (FDA) as an add-on maintenance treatment for patients with severe asthma, age 18 and ... Read more

March 16, 2016March 16, 2016

People with Severe Asthma Are Focus of Study to Better Target Treatment of XolairR

Asthma, News

A new study developed by researchers at the National Institute for Health Research (NIHR) Southampton Respiratory Biomedical Research Unit in England and managed by the NIHR-funded Clinical Trials Unit at the University of ... Read more

February 15, 2016February 18, 2016

Potential Target for Severe Asthma, Other Chronic Inflammatory Diseases Identified

Asthma, News

In a new study, researchers identified the role of platelets in the immune response, and discovered that the platelet-derived protein Dickkopf-1 (Dkk-1) contributes to chronic inflammation, having a pathological role in ... Read more

November 6, 2015November 6, 2015

GSK’s Nucala Approved for Use in Patients with Severe Asthma

Asthma, News

Nucala (mepolizumab) was approved by the U.S. Food and Drug Administration (FDA) on Nov. 4 as an add-on medication, used in combination with other medications, to maintain asthma control in patients ... Read more

October 2, 2015November 6, 2015

Pieris Pharmaceuticals’ Inhaled IL4Ra Antagonist Shows Promise As Severe Asthma Therapy

Asthma, News

Professor Gary Anderson, PhD, FThorSoc, FERS, and Director of the Lung Health Research Centre at the University of Melbourne recently revealed preclinical data related to PRS-060, Pieris Pharmaceuticals’ new inhaled ... Read more

September 30, 2015November 6, 2015

Severe Asthma Takes Control of Everyday Life, Boston Scientific Patient Survey Shows

Asthma, News

Boston Scientific recently conducted an extensive patient survey that sought to better understand the impact asthma has made and continues to make on the lives of more than 850 patients ... Read more

July 23, 2015November 6, 2015

Synairgen Announces Initiation of AstraZeneca’s Phase II Trial of AZD9412 for Severe Asthma

Asthma, News

Synairgen, a drug discovery and development company focused on advancing novel approaches for severe respiratory conditions recently announced that AstraZeneca has initiated its Phase IIa clinical trial of AZD9412. The drug, ... Read more

July 20, 2015November 6, 2015

AstraZeneca Signs Partnership With Kyowa Hakko Kirin To Commercialize Asthma and COPD Drug Benralizumab in Japan

Asthma, News

AstraZeneca announced last week it has signed into a partnership with Kyowa Hakko Kirin Co. Ltd. for exclusivity in commercializing benralizumab, a monoclonal antibody currently in Phase III clinical studies as potential ... Read more