Cystic Fibrosis

February 14, 2018February 14, 2018

FDA Approves Vertex’s Symdeko to Treat CF Patients 12 and Older

Cystic Fibrosis

The U.S. Food and Drug Administration (FDA) has approved the third targeted therapy developed by Vertex Pharmaceuticals for patients with cystic fibrosis (CF). Symdeko can now be used in the United ... Read more

February 5, 2018February 5, 2018

Vertex Selects VX-659 and VX-445 for Two CF Triple Combo Regimens

Cystic Fibrosis

Vertex Pharmaceuticals has selected two of its next-generation correctors, VX-659 and VX-445, for Phase 3 trial development as part of two triple combination regimens for the treatment of cystic fibrosis. This ... Read more

January 12, 2018January 12, 2018

European Union Approves Orkambi Use for Children 6-11 Years Old

Cystic Fibrosis, News

The European Commission has granted Vertex Pharmaceuticals an extension of the marketing authorization for Orkambi (lumacaftor/ivacaftor) to include children 6-11 years old who have cystic fibrosis (CF) caused by two copies ... Read more

January 9, 2018January 9, 2018

Proteostasis’ Planned Trial of Triple Combo CF Therapy Supported By Advocacy Groups in US, Europe

Cystic Fibrosis, News

The drug development arms of two leading cystic fibrosis (CF) organizations, one in the U.S. and one in Europe, have endorsed Proteostasis Therapeutics’ coming trial of a triple combination therapy ... Read more

January 3, 2018January 3, 2018

Kalydeco Seen As Safe in Treating CF in Young Children, Ages 1 to 2, Study Data Show

Cystic Fibrosis, News

Kalydeco (ivacaftor) was shown to be safe and well-tolerated in 1- and 2-year-old children with cystic fibrosis (CF), based on data from a Phase 3 trial, Vertex Pharmaceuticals announced. Additionally, trial ... Read more

December 6, 2017December 12, 2017

Former Football Player Helping CF Patients Obtain AffloVest Airway-clearing Devices

Cystic Fibrosis, News

A former American football player’s foundation is teaming up with AffloVest to provide one of the company’s airway-clearing devices to a cystic fibrosis patient in each of the 50 states. The partners are ... Read more

November 27, 2017November 27, 2017

New York’s Montefiore Einstein Center Launches Lung Transplant Program

COPD, Cystic Fibrosis, Idiopathic Pulmonary Fibrosis, News

New York City’s Montefiore Einstein Center for Heart & Vascular Care has received interim approval from the United Network for Organ Sharing (UNOS) to launch its new lung transplant program. Lung transplant ... Read more

October 12, 2017October 13, 2017

Vibativ Displays More Punch Against Bacteria Than Other Antibiotics, Studies Show

Cystic Fibrosis, News, Pneumonia

Vibativ (telavancin) displays more punch against the Staphylococcus aureus bacteria that is involved in lung diseases than other antibiotics it has been tested against, according to presentations in San Diego this month. This ... Read more

October 10, 2017October 10, 2017

Duke Undergrads to Do Medical Research, Including Developing Tool to Spot CF Infections

Cystic Fibrosis, News

Two teams of Duke University undergraduates will be doing health research that is normally the purview of graduate students and professors, including a cystic fibrosis infections project. The 13 students from the Center ... Read more